INTENDED FOR HEALTHCARE PROFESSIONALS

Backed by a Body of Evidence  

INTENDED FOR HEALTHCARE PROFESSIONALS

Backed by a Body of Evidence  

ECHELON products are designed for exceptional tissue management and control. It's the only portfolio that goes "beyond the benchtop," using real-world evidence in colorectal, bariatric and thoracic surgery to support innovative performance and design for a better way to staple.
 

Backed by a Body of Evidence
Echelon Circular Evidence Overview

Colorectal Evidence

Watch a quick overview of the evidence supporting the ECHELON CIRCULAR™ Powered Stapler.
 

The ECHELON CIRCULAR™ Powered Stapler is demonstrated through clinical and real-world evidence and was associated with superior results in colorectal surgery vs. manual circular staplers.1


1.8%

anastomotic leak rate delivered by ECHELON CIRCULAR™ in a prospective, single-arm clinical study conducted at 12 institutions across the US and Europe2
 

1.7%

anastomotic leak rate demonstrated by ECHELON CIRCULAR™ in an independent cohort study conducted at University Clinic Hospital of Valencia (Spain)3
 

Learn more about the evidence

Surgeon Testimonial

Surgeon Testimonial

Impacting outcomes in colorectal surgery

Impacting outcomes in colorectal surgery
 

Summary of key data points from publications
 

Demonstrated in clinical and real-world evidence

Demonstrated in clinical and real-world evidence
 

Four study publications focused on the ECHELON CIRCULAR™ Powered Stapler.
 

Optimized perfusion

Optimized perfusion4
 

Reduced leaks at the staple line without compromising perfusion4
 

ECHELON CIRCULAR is the only circular stapler that is backed by large-scale real-world evidence in colorectal surgery5. When compared with manual circular staplers, ECHELON CIRCULAR was associated with:


74%

reduction in anastomotic leak rates1(1.8% vs 6.9%, p<0.001)
 

44% 

reduction in inpatient re-admission rates6(6.1% vs 10.8%, p=0.019)
 

67%

reduction in ileus bowel obstruction rates7(6.1% vs 19.5%, p<0.001)
 

ECHELON CIRCULAR Powered Stapler: An innovative combination of technologies  

A Better Way to Staple

A Better Way to Staple
 

Two innovative stapling technologies provided significantly fewer leaks at the staple line and greater perfusion throughout the entire stapled region compared to the Medtronic EEA™ Circular Stapler with Tri-Staple™ Technology.8
 

Gripping Surface Technology & 3D Stapling Technology

Gripping Surface Technology & 3D Stapling Technology
 

GST provided gentler tissue handling with a 33% reduction in compressive forces on tissue9.
3D Stapling Technology evenly distributed compression and reduced potential leak paths10.
 

Powered for Stability

Powered for Stability
 

Powered firing increased stability with 37% less distal tip movement during firing, and reduced force to fire by 97%11.
 

Body of Evidence: Bariatric

Body of Evidence: Bariatric
 

The ECHELON FLEX™ Powered Plus Stapler with GST Reloads is backed by retrospective studies demonstrating associated reductions in hemostasis-related complications and hospital costs.11 It is designed with multi-stage compression to reduce the forces exerted on the tissue during firing.
 

Body of Evidence: Thoracic

Body of Evidence: Thoracic
 

The ECHELON FLEX™ Powered Vascular Stapler plus ECHELON FLEX™ Powered Stapler with GST has been shown through retrospective studies to be associated with the reduction of complications without an increase in price.13 GST offers two-stage compression and stability while PVS offers improved access and precision via a narrow anvil, increased articulation, and smaller shaft diameter for vascular firings.
 

References

1.    A retrospective matched analysis of 165 Echelon Circular cases from clinical study, and 1,348 manual circular stapler cases from Premier Healthcare Database [ECHELON CIRCULAR 1.8% (3/165) vs. manual circular 6.9% (93/1348) for anastomotic leaks, p<0.001

2.    A Prospective, Multi‐ Center Evaluation of the ECHELON CIRCULAR Powered Stapler in Left‐Sided Colorectal Anastomoses, N=168

3.    Impact of the Novel Powered Circular Stapler on Risk of Anastomotic Leakage in Colorectal Anastomosis. A Propensity Score‐ Matched Study. [ECHELON CIRCULAR 1.7% (1/60) vs. manual circular 11.8% (14/119), p=0.022]

4.    Benchtop testing in porcine tissue ≤30mmHg (26mmHg average pressure experienced during intra-operative leak test), comparing Ethicon CDH29P to Medtronic EEA2835 (p<0.001) and preclinical perfusion model, in which perfusion was not significantly different between devices

5.    Large-scale is defined as sample size greater than 1500 cases.

6.    A retrospective matched analysis of 165 Echelon Circular cases from clinical study, and 1,348 manual circular stapler cases from Premier Healthcare Database [ECHELON CIRCULAR 6.1% (10/165) vs. manual circular 10.8% (146/1348), p=0.019]

7.    A retrospective matched analysis of 165 Echelon Circular cases from clinical study, and 1,348 manual circular stapler cases from Premier Healthcare Database [ECHELON CIRCULAR 1.8% (3/165) vs. manual circular 9.2% (124/1348), p<0.001]

8.    Benchtop testing in porcine tissue at <34mmHg, comparing number of leaks of 11 for ECHELON CIRCULAR Powered Stapler (CDH29P) (n=30) to 21 for Medtronic EEA™ Circular Stapler with Tri-Staple™ Technology (TRIEEA28MT) (n=30), p<0.05, and preclinical perfusion model comparing means of 0.35085 (n=23) for CDH29P to 0.32665 (n=23) for TRIEEA28MT, p < 0.05

9.    Benchtop testing on porcine colon measuring compressive forces during closure, comparing means of 8.22 lbf for Ethicon CDH29P (n=15) to 13.25 lbf for Medtronic TRIEEA28MT (n=15), p<0.01.

10.    Staple line analysis in benchtop testing, comparing system standard deviation of pressure of 1.49 for CDH31P to 2.05 for Medtronic TRIEEA31MT.

11.    Users firing in a porcine model, comparing Ethicon CDH29P to Medtronic EEA2835, p=0.003.

12.    Based on literature search performed May 2019. Large-scale is defined as sample size greater than 3500 cases.

13.    Miller DL, Roy S, Kassis ES, Yadalam S, Ramisetti S, Johnston SS. Impact of powered and tissue-specific endoscopic stapling technology on clinical and economic outcomes of video-assisted thoracic surgery lobectomy procedures: a retrospective, observational study. Adv Ther. 2018;35(5):707-723.