You are about to leave jnjmedtech.com. By clicking to continue, you will be taken to a web site governed by their own Legal and Privacy Policies.
Surgical bleeding can adversely affect patient outcomes, hospital costs and resources

Up to 68% of cases in open procedures experience disruptive bleeding events despite the use of haemostats1

Challenging and uncontrollable bleeding during surgery is associated with increased mortality rates1,2

Complications related to surgical bleeding may increase resource utilization3-7
Compared to primary methods of hemostasis alone, adjunctive hemostats have been associated with reduced use of hospital resources in the following ways:

Up to 35% fewer patients require blood transfusions8-13

Up to 4 days shorter length of hospital stay8-15

Up to 25 minutes reduced operating time14-15
References
*Compared to primary methods of hemostasis alone (117999-190704 EMEA)
1. Corral, Health and economic outcomes associated with uncontrolled surgical bleeding: a retrospective analysis of the Premier Perspectives Database, Clinico Economics and Outcomes Research;2015;7;409
2. Marietta M, Facchini L, Pedrazzi P, Busani S, Torelli G. Pathophysiology of bleeding in surgery.2006; Transplant Proc 38 (3):812-814
3. Stokes, Impact of bleeding-related complications and or blood product transfusions on hospital costs in inpatient surgical patients, BMC Health Services Res;2011;11;135
4. Kahn, Cost Savings Attributable to Reductions in Intensive Care Unit Length of Stay for Mechanically Ventilated Patients, Med Care;2008;46;1226
5. Dasta, Daily cost of an intensive care unit day The contribution of mechanical ventilation, Crit Care_Med;2005;33;1266
6. Toner, Costs to Hospitals of Acquiring and Processing Blood in the US A Survey of Hospital-Based Blood Banks and Transfusion Services, Appl Health Econ Health Policy;2011;9;29
7. Al-Attar,Impact of bleeding complications on length of stay and critical care utilization in cardiac surgery patients in England,Journal of Cardiothoracic Surgery;2019;14;64
8. Notarnicola A, Moretti L, Martucci A, Spinarelli A, Tafuri S, Pesce V, Moretti B. Comparative efficacy of different doses of fibrin sealant to reduce bleeding after total knee arthroplasty. Blood Coagul Fibrinolysis. 2012; 23 (4):278-284
9. Molloy DO, Archbold HA, Ogonda L, McConway J, Wilson RK, Beverland DE. Comparison of topical fibrin spray and tranexamic acid on blood loss after total knee replacement: a prospective, randomised controlled trial. J Bone Joint Surg
Br. 2007; 89 (3):306-309.
10. Sabatini L, Trecci A, Imarisio D, Uslenghi MD, Bianco G, Scagnelli R. Fibrin tissue adhesive reduces postoperative blood loss in total knee arthroplasty. J Orthop Traumatol. 2012; 13 (3):145-151.
11. Wang GJ, Hungerford DS, Savory CG, Rosenberg AG, Mont MA, Burks SG, Mayers SL, Spotnitz WD. Use of fibrin sealant to reduce bloody drainage and hemoglobin loss after total knee arthroplasty: a brief note on a randomized
prospective trial. J Bone Joint Surg. 2001. 83-A (10):1503-1505.
12. Randelli F, Banci L, Ragone V, Pavesi M, Randelli G. Efectiveness of fibrin sealant after cementless total hip replacement: a double-blind randomized controlled trial. Int J Immunopathol Pharmacol. 2013; 26 (1):189-197.
13. Joseph T, Adeosun A, Paes T, Bahal V. Randomised controlled trial to evaluate the efficacy of TachoComb H Patches in Controllin PTFE Suture-hole Bleeding. Eur J Vasc Endovasc Surg. 2004; 27, 549-552.
14. Pan HW, Zhong JX, Jing CX. Comparison of fibrin glue versus suture for conjunctival autografting in pterygium surgery: a meta-analysis. Ophthalmology. 2011; 118 (6):1049-1054.
15. Dancey AL, Cheema M, Thomas SS (2010) A prospective randomized trial of the efficacy of marginal quilting sutures and fibrin sealant in reducing the incidence of seromas in the extended latissimus dorsi donor site. Plast Reconstr Surg
125 (5):1309-1317.
16. Ferko N, Danker W, Gangoli G. A systematic approach to surgical hemostat use supports standardization and cost efficiencies. Healthcare Purchasing News. 2017; 41 (11):34-35.
17. Hong YM, Loughlin KR. The use of haemostatic agents and sealants in urology. J Urol. 2006;176 (6 Pt 1):2367-2374
18. Ethicon, 20110131 IMS Hospital Supply Index Ethicon US BIOSURGERY Hospital, Jan 2011, Data on File.
19. Spotnitz, Fibrin Sealant Patches; powerful and easy-to use hemostats.Open Access Surgery,2014. 71-79