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The Use of Intracardiac Echocardiography (ICE) Catheters in Endocardial Ablation of Cardiac Arrhythmia: Meta-Analysis of Efficiency, Effectiveness, and Safety Outcomes
Goya, Masahiko, et al. J Comp Eff Res. January 2020. doi: 10.1111/jce.14367

Objective
Compare use of ICE during catheter ablation of cardiac arrhythmias affect outcomes compared to ablation without the use of ICE

Methods
- Systematic literature review and meta-analysis
- 19 studies identified
- 2,186 total patients included

Results
Use of ICE was associated with a significant:
- 6.95 mean reduction in fluoroscopy time
- 15.2 mean reduction in procedure time
- Reduction in fluoroscopy dose
Predictors of Cardiac Perforation with Catheter Ablation of Atrial Fibrillation
Friedman, Daniel, et al. JACC EP. March 2020. DOI:10.1016/j.jacep.2020.01.011

Objective
Identify factors associated with the occurrence of cardiac perforation caused during a catheter ablation procedure for atrial fibrillation

Methods
Retrospective, observational cohort study
Data from the Medicare Standard Analytic File was used
Logistic regression was used to assess predictors of cardiac perforation

Results
- 1.3x greater odds of perforation for female sex
- 1.4x greater odds of perforation for obesity
- 4.9x lower odds of perforation with use of ICE
- 0.1x lower odds of perforation with prior cardiac surgery
Real-world Outcomes of Ventricular Tachycardia Catheter Ablation with Versus Without Intracardiac Echocardiography
Field ME, Gold MR, Reynolds MR, et al. J Cardiovasc Electrophysiol. 2019 Dec 23 doi:10.1111/jce.14324

Objective
Assess differences in outcomes between ventricular tachycardia (VT) patients undergoing catheter ablation with versus without the use of intracardiac echocardiography (ICE).

Methods
- Retrospective, observational cohort study
- Data from the IBM MarketScan Commercial and Medicare Supplemental databases were used
- Comparison using propensity-score matching and regression analysis

Results
As compared to the non-ICE cohort, at 12-month follow-up, the ICE cohort was associated with:
- 24% lower odds of VT-related readmission
- 30% lower odds of repeat VT ablation
Catheter Ablation of Atrial Fibrillation with and Without On-Site Cardiothoracic Surgery
Friedman, Daniel J et al. J Am Coll Cardiol. 2019 May 21. doi:10.1016/j.jacc.2019.02.036

Objective
Assess the relationship between the presence or absence of on-site cardiothoracic surgery (CTS) units, with 30-day rates of cardiac perforation, CTS, re-hospitalization, and death

Methods
- Retrospective, non-randomized database study
- Data from the Medicare Standard Analytic File was used
- Comparison using propensity-score matching and regression analysis

Results
There was no significant difference between the presence or absence of CTS units and rates of cardiac perforation, CTS, re-hospitalization, and death.
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