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  1. Home
  2. Products
  3. DERMABOND® PRINEO® Skin Closure System

DERMABOND® PRINEO® Skin Closure System

DERMABOND® PRINEO® combines the proven strength, flexibility, and microbial barrier of DERMABOND ADVANCED® with the security of a self-adhering mesh to facilitate skin closure and an optimal healing environment.1-6

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Instructions for Use

Instructions for use are found in the information that accompanied the product packaging.

See DERMABOND PRINEO System in Action
Patient Care Instructions
DERMABOND® PRINEO® Skin Closure System
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Features & Benefits

Readmission Rates DERMABOND PRINEO Skin Closure System v. Staples

Shorter length of stay and fewer return visits

DERMABOND® PRINEO® has no dressings to change or staples to remove. Patients with DERMABOND® PRINEO® had a shorter length of stay and lower readmissions than patients with skin staples in total knee arthroplasty.7* 

DERMABOND PRINEO Skin Closure System - caring for your incision at home

Simplified at-home care

With its transparent barrier that allows for observation of the incision, DERMABOND® PRINEO® may be especially suitable for surgeons who have adopted telemedicine protocols in their post‐op patient care. Patients may be able to shower immediately after their procedure, if directed by the healthcare professional.4

Microbial barrier

Microbial barrier

The microbial barrier protection of DERMABOND® PRINEO® is proven 99% effective through 72 hours in vitro.8 Furthermore, DERMABOND® PRINEO® is demonstrated in vitro to kill 99.9% of bacteria (MRSA, MRSE, and E Coli) on direct contact.9,11

dermabond prineo skin holding strength graph

Stronger, more secure closure

DERMABOND® PRINEO® was shown to provide statistically significant greater skin holding strength than skin staples or subcuticular suture.10,12

Videos

Resources

Total Abdominal Hysterectomy with Dr. Thad Denehy

Total Abdominal Hysterectomy with Dr. Thad Denehy

02:52

Anterior Spine Surgery with Dr. Christopher Cain

Anterior Spine Surgery with Dr. Christopher Cain

04:33

Total Abdominal Hysterectomy with Dr. Thad Deheny

Total Abdominal Hysterectomy with Dr. Thad Deheny

02:52

Patient Journey: Watch Diane's experience with DERMABOND® PRINEO®

Patient Journey: Watch Diane's experience with DERMABOND® PRINEO®

03:32

Supporting Documentation

Product Support

DERMABOND® PRINEO® Skin Closure System Brochure

Download PDF

DERMABOND PRINEO System 22 Information Sheet

Download PDF

DERMABOND® PRINEO® Complies with Guidelines for Resuming Elective Surgery During the Pandemic

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DERMABOND® PRINEO® in Labor and Delivery

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DERMABOND PRINEO Skin Closure System Optimal Device Performance Guide

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Clinical Evidence

DERMABOND® PRINEO® Skin Closure System Evidence Brief

Download PDF

DERMABOND PRINEO Patient Surgeon Satisfaction Study

Download PDF

DERMABOND® PRINEO® C-section Study

Download PDF

DERMABOND® PRINEO® FAQ

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DERMABOND PRINEO Dermatitis Study Stat

Download PDF

DERMABOND PRINEO Total Knee Arthroplasty Study

Download PDF

C-Section Value Brief

Download PDF

Dr. Snyder/TriHealth Case Study

Download PDF

Proliance Case Study

Download PDF

Wound Closure Procedures

Total Knee Arthroplasty
Total Hip Arthroplasty
Open Ventral

References

*In a retrospective, observational study using the Premier Healthcare Database in total knee arthroplasty (N=1,942), 2012-2015; LOS 2.8 days vs 3.2, P=0.002; discharge to SNF 26% vs 39%, P=0.011; 30-day readmissions 1.8 vs 4.4%, P=0.006).

1. Keplinger S. Protocol investigation of the comparison of PRINEO with conventional wound closure techniques. 07PD048. May 2007. Ethicon, Inc.

2. Richter D. Multi-centre study to show equivalence of DERMABOND PROTAPE to INTRADERMAL SUTURES for skin closure of full thickness surgical incisions associated with breast procedures. 07CS003. Final Report 09 July 2010. Ethicon, Inc.

3. Richter D. Multi-centre study to show equivalence of DERMABOND PROTAPE to INTRADERMAL SUTURES for skin closure of full thickness surgical incisions. 06CS005. Final Report 10 June 2010. Ethicon, Inc.

4. DERMABOND® PRINEO® Skin Closure System (22 cm), Instructions for Use. Ethicon, Inc.

5. Shapiro AJ, Dinsmore RC, North JH. Tensile strength of wound closure with cyanoacrylate glue. Am Surg. 2001;67(11):1113-1115. 

6. Kannon GA, Garrett AB. Moist wound healing with occlusive dressings. A clinical review. Dermatol Surg. 1995;21(7):583-590.

7. Sutton N, Schmitz ND, Johnston SS. Economic and clinical comparison of 2-octyl cyanoacrylate/polymer mesh tape with skin staples in total knee replacement. J Wound Care. 2018;27(Sup4):S12-S22.

8. Su W. Study Report for in vitro evaluation of microbial barrier properties of DERMABOND ProTape. Report Number 06TR071. December 4, 2006. Ethicon, Inc.

9. Bhende S. In-vitro study to evaluate the ability of DERMABOND™ PRINEO™ Skin Closure System to kill bacteria on contact. June 22, 2012. Ethicon, Inc.

10. Kumar A. Study to Compare the tissue holding strength of PRINEO™ skin closure system with conventional wound closure techniques. AST-2012-0290. 2012. Ethicon, Inc.

11. Clinical significance unknown.

12. In an ex vivo study, more load in N was required to create a 3 ±1 mm gap between skin edges approximated with DERMABOND PRINEO System, than with subcuticular 4-0 MONOCRYL® Suture or PROXIMATE® Ethicon Endo-Surgery skin staples (P=0.00).

2021 Ethicon Product Catalog


© Ethicon US, LLC. 2019.
For complete indications, contraindications, warnings, precautions, and adverse reactions, please reference full package insert.
This site is published by Ethicon US, LLC, which is solely responsible for its contents, and is intended for U.S. audiences only.
This site is intended for Healthcare Professionals. If you are a patient, it is important that you discuss information about the benefits and risks of products with your doctor.
Last updated February 20, 2019. The third-party trademarks used herein are trademarks of their respective owners. Data and usage fees may apply. See your carrier for more information.

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