Skip to main content

Intended for Healthcare Professionals

Johnson and Johnson logo graphic link
/en-US
  • acclarent logo
  • biosense webster logo
  • cerenovus jjmdc logo
  • DePuy Synthes
  • Ethicon Logo
  • Mentor Logo

Intended for HCPs

Intended for Healthcare Professionals

Secondary nav block

DePuy Synthes Logo
  • Specialties
    • All Specialties
    • Craniomaxillofacial (CMF)
    • Foot & Ankle
    • Hip
    • Knee
    • Shoulder
    • Spine
    • Sports Medicine
    • Trauma & Extremities
    • Veterinary
  • Procedures
    • All Procedures
    • Hip
      • Hip Arthroplasty
    • Knee
      • Anterior Cruciate Ligament Reconstruction (ACL) Soft Tissue
      • Knee Replacement
      • Sports Medicine
        • BTB ACL Reconstruction
    • Sports Medicine
      • Arthroscopic Anatomic Glenoid Reconstruction
      • BTB ACL Reconstruction
      • Lower Trapezius Transfer
  • Product Hub
  • Services
    • All Services
      • Investigator-Initiated Studies
      • J&J Innovation
    • ASC Capabilities
    • Advance Case Management
    • Loaner Program
    • MatrixRIB Care Program
    • Service Care
  • News
  • Patients
    • Knee Replacement
    • Patient Home
    • VELYS Patient Home
  1. Home
  2. Products
  3. ViviGen® & ViviGen Formable® Cellular Bone Matrix

ViviGen® & ViviGen Formable® Cellular Bone Matrix

ViviGen® & ViviGen Formable® Cellular Bone Matrix

ViviGen is a cellular allograft intended for repair or reconstruction of musculoskeletal defects. ViviGen is being utilized in fusion, nonunion, and malunion for foot/ankle or long bone trauma in patients with compromised biology.6- 11* It is comprised of three components that work in tandem to deliver superior healing potential compared to MSCs.1,2,3

1. Osteogenic ( Lineage Committed Bone Cells)The processing of ViviGen removes bone marrowcomponents including Mesenchymal Stem Cells whileretaining the desirable bone cells (osteoblasts,osteocytes and bone lining cells).1

2. Osteoconductive ( Corticocancellous Chips)Provide a natural scaffold for cell attachment, migrationand proliferation.1

3. Osteoinductive ( Demineralized Bone)A patented demineralization process exposes natural growth factors within the bone matrix that recruit hostcells and stimulate bone forming activity.1*

Results from case studies are not predictive of results in other cases. Results in other cases may vary. ViviGen is a registered trademark of LifeNet Health.The third party trademarks used herein are the trademarks of their respective owners.

Get in Touch with a Sales Consultant
vivigen cellular bone matrix product

IMAGES

vivigen cellular bone matrix product

Key Resources

paper with exclamation mark icon

Instructions for Use

View Instructions PDF

Unfortunately we can’t detect an electronic copy of the Instructions for Use (IFU) you are seeking. You can find instructions on how to use this product included with the product packaging.

If you need an additional copy of the IFU, you can:

  1. Search the global e-ifu.com website, 
  2. Contact your sales consultant, or 
  3. Reach out to us directly.

Features & Benefits

Osteogenic1

Contains viable, lineage committed bone cells that areable to proliferate in vitro post cryopreservation and thaw4

Osteoconductive1

Contains corticocancellous chips that provide a naturalscaffold for cell attachment, cell migration and cellproliferation1

Osteoinductive1

Demineralization of the cortical bone exposes thenatural growth factors within the matrix1

Safety

Every lot is aseptically processed and tested for sterilityusing USP <71>1

Packaging

The rapid heat transfer not only allows for all sizes tothaw in less than 5 minutes, but is also vital for cellviability5

Processing Time

ViviGen reaches cryopreservation within 72 hours maximizing cell viability 24 hours sooner than competitive products1

Maximized Cell Viability

The processing of ViviGen is focused on protecting viable, lineage committed bone cells from recovery to implantation1

Multiple Forms

ViviGen and ViviGen Formable provide a comprehensive solution to meet surgeons’ clinical needs

Supporting Documentation

Resources Specifications
Resources
Specifications

Resources

  • ViviGen Clinical Compendium
    PDF Icon

    View PDF

  • ViviGen®/ViviGen Formable® Sell Sheet- TRAUMA
    Link Icon

    Download PDF

  • Select all documents (2)

Specifications

BL-1500-001   1cc 
BL-1500-002   5cc 
BL-1500-003   10cc 
BL-1500-004   15cc 
BL-1600-001   Small 
BL-1600-002   Medium 
BL-1600-003   Large 
BL-1600-004   X-Large 

References

  1. LifeNet Health Data on File DHF 12-008, DHF 15-001, CC#52268.
  2. Reichert et al. Ovine coritical osteoblasts outperformbone marrow cells in an ectopic bone assy. J Tissue EngRegen Med 2011; 5:831-844.
  3. Tortelli, et al. The development of tissue-engineeredbone of different origin through endochondral andintramembranous ossification following the implantationof mesenchymal stem cells and osteoblasts in a murinemodel. Biomaterials 2010; 31:242-249.
  4. Sachs, Chen. Osteogenic Potential of the ViviGen CellularComponent Results from In Vitro Studies.
  5. Chen. Advantage of ViviGen Packaging Results from InVitro Studies.
  6. 68-20-210: K. Apostle, “Surgical Repair of Open FemurFracture with Bone Loss Using ViviGen® Cellular BoneMatrix”, 2018.
  7. 68-20-224: A. Kaz, “Surgical Repair of a Tibial Metaphysial Defect Using ViviGen Formable® CellularBone Matrix”, 2019.
  8. 68-20-226: A. Kaz, “Surgical Repair of Severe Varus Ankle Deformity with Osteoarthritis Using ViviGenCellular Bone Matrix”, 2019.
  9. 68-20-227: A. Kaz, “Surgical Repair of a Nonunion Fracture at the Fifth Metatarsal Using ViviGen CellularBone Matrix”, 2019.
  10. 10. 68-20-237: W. Giessler, “Surgical Repair of a Delayed Union to the Radius Diaphysis Using ViviGen® CellularBone Matrix in a Division I Football Athlete”, 2019.
  11. 68-20-238: W. Giessler, “Salvage of Failed Wrist Arthroplasty Using ViviGen® Cellular Bone Matrix”, 2019.

ViviGen & ViviGen Formable are registered trademarks of LifeNet Health.

Indication Statement

ViviGen is intended for repair or reconstruction of musculoskeletal defects.

120443-190808 DSUS

© DePuy Synthes 2022. All Rights Reserved. This site is published by the DePuy Synthes Companies, which are solely responsible for its content. This site is governed solely by applicable U.S. laws and governmental regulations. This site is for visitors from the United States. The third party trademarks used herein are the trademarks of their respective owners.

DePuy Synthes Logo

About

-

  • About Us
  • Our History
  • News & Media
  • Grants & Giving
  • Innovation Center

Useful Links

-

  • Instructions for Use (IFU)
  • Johnson & Johnson Institute
  • Reimbursement Resources
  • Investigator Initiated Studies

Legal

-

  • CA Compliance
  • ASR Recall

Connect

-

  • . . . .
  • Contact Us
  • Online Ordering
  • Inventory Management (eSIMS)
  • Careers
Johnson and Johnson logo
Johnson & Johnson
  • Privacy Policy
  • Legal Notice
  • Do Not Sell or Share My Personal Information
  • Contact Us
  • J&J Institute
  • Accessibility Statement
  • Cookie Policy
English (United States)

© Medical Device Business Services, Inc. 2021-2023. All rights reserved.

This information is intended for use by customers, patients, and healthcare professionals in the United States only. We recognize that the Internet is a global communications medium; however, laws, regulatory requirements, and product information for medical products can vary from country to country. The product information included here may not be appropriate for use outside the United States, and the information from other sites you visit may not be appropriate for use in the United States.

You are about to leave jnjmedtech.com. By clicking to continue, you will be taken to a web site governed by their own Legal and Privacy Policies.

Yes, Continue to External Site No, Stay Here