Sports Medicine

ORTHOVISC™ High Molecular Weight Hyaluronan

Product Codes:

277500

Sports Medicine

ORTHOVISC™ High Molecular Weight Hyaluronan

Product Codes:

277500

ORTHOVISC™ High Molecular Weight Hyaluronan is a non-avian sourced hyaluronic acid injection therapy that has up to six months of clinically proven efficacy with 3 or 4 injections.1

About This Product

ORTHOVISC is a sterile, non-pyrogenic, clear, viscoelastic solution of hyaluronan contained in a single-use syringe1:

  • Provides more HA to the joint than any other multi-injection HA product1-2
  • Provides pain relief for osteoarthritis of the knee that lasts up to 6 months1
  • Has a safety profile similar to placebo in clinical studies1

Features & Benefits

High HA Content

Provides more HA to the joint than any other multi-injection product.1 -2

Improvement in Knee Pain

Improvement in pain and function that lasts up to 6 months.1

Safety Profile

Similar to saline demonstrated in clinical trials even during retreatment.1

Product Resources

Clinical Resources

References

  1. ORTHOVISC [package insert]. Bedford, MA: Anika Therapeutics, Inc., 2020
  2. Euflexxa [package insert]. Parsippany, NJ: Ferring Pharmaceuticals Inc., 2016
  3. Gelsyn-3 [package insert]. Durham, NC: Bioventus; 2016
  4. Synvisc (Hyalgan G-F 20) [package insert]. Ridgefield, NJ: Genzyme Biosurgery; 2020
  5. Hyalgan [package insert]. Parsippany, NJ Fidia Pharma USA Inc.; 2014
  6. Supartz FX [package insert]. Durham, NC: Bioventus; 2015
  7. TriVisc [package insert]. Doylestown, PA: OrthogenRx, Inc.; 2017
  8. Hymovis [package insert]. Parsippany, NJ Fidia Pharma USA Inc.; 2015
  9. GenVisc 850 [package insert]. Doylestown, PA: OrthogenRx, Inc.; 2015
  10. Visco-3 [package insert]. Tokyo, Japan: Seikagaku Corp.; 2017

ORTHOVISC™ High Molecular Weight Hyaluronan is indicated in the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy and to simple analgesics, e.g., acetaminophen. In clinical studies, the most commonly reported adverse events were arthralgia, back pain, and headache. Other side effects included local injection site adverse events. ORTHOVISC™ is contraindicated in patients with known hypersensitivity to hyaluronate formulations or known hypersensitivity (allergy) to gram positive bacterial proteins. ORTHOVISC™ should not be injected in patients with infections or skin diseases in the area of the injection site. Intra-articular injection of sodium hyaluronate preparations has occasionally been associated with allergic/anaphylactic reactions and transient hypotension, which have generally resolved spontaneously or after conservative treatment. ORTHOVISC™ is manufactured by and is a registered trademark of Anika Therapeutics, Inc.

All medical devices have associated risks. Please refer to the package insert and other labeling for a complete list of indications, contraindications, precautions and warnings. For further information on DePuy Synthes Products, please contact your local DePuy Synthes Representative

Please refer to the Instructions For Use for a complete list of indications, contraindications, warnings and precautions. The third-party trademarks used herein are the trademarks of their respective owners.

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