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Ethicon is leading advancements in wound closure with products that are transforming surgery and improving patient outcomes. Our products are designed to:
IMPROVE
patient healing
MINIMISE
the risk of complications
REDUCE
operative time to improve hospital efficiencies
Featured Products

DERMABOND® PRINEO® Skin Closure System
The only skin closure device that combines the proven strength, flexibility, and antimicrobial protection of DERMABOND® Topical Skin Adhesive with the added support and security of a self-adhering mesh to further facilitate both wound-edge approximation and an optimal healing environment, which may be particularly useful in surgeries such as hip and knee arthroplasty as well as caesarean section.1-2

STRATAFIX™ Knotless Tissue Control Devices
STRATAFIX™ barbed closure devices deliver more efficiency and strengthƗ than traditional suturing – without knot-related complications.2-4 Compared to traditional sutures,4-6 STRATAFIX™ reduced length of stay7 and time in operating room.3

Plus Antibacterial Sutures
Ethicon’s Plus Antibacterial Sutures are the only triclosan-coated sutures commercially available worldwide and are backed by a large body of evidence.8-20 Meta-analysis showed a 28% reduction in surgical site infection (SSI) risk with triclosan-coated.21§|| Triclosan-coated sutures are endorsed by global health authorities.22-26
References
*As shown in a study comparing STRATAFIX® Knotless Tissue Control Device with conventional sutures in spinal surgery.
†Refers to STRATAFIX™ Symmetric PDS™ Plus Knotless Tissue Control Device only.
‡Guidelines on reducing the risk of surgical site infections are general to triclosan-coated sutures and are not specific to any one brand.
§In a meta-analysis of 21 randomised clinical trials (RCTs), 6462 patients, 95% Cl: (14, 40%), P<0.001.
||All triclosan-coated sutures in these RCTs were Ethicon Plus Antibacterial Sutures (MONOCRYL® Plus Antibacterial [poliglecaprone 25) Suture, Coated VICRYL® Plus Antibacterial [polyglactin 910) Suture, and PDS® Plus Antibacterial [polydioxanone] Suture).
- Ethicon Inc. DERMABOND® PRINEO® Skin Closure System (22 cm) Instructions for Use. LAB100114233v2. 5/15.
- Data on File. Ethicon, Inc. Su. 06TR071 Study Report for in vitro evaluation of microbial barrier properties of DERMABOND ProTape. (Claim 043324-151113).
- Johnston S, Chen B, Tommaselli G, Jain S, Pracyk J. Barbed and conventional sutures in spinal surgery patients: an economic and clinical outcomes comparison. J Wound Care. 2020;29(5):S9-S20.
- Moran ME, Marsh C, Perrotti M. Bidirectional-barbed sutured knotless running anastomosis v classic Van Velthoven suturing in a model system. J Endourol. 2007;21(10):1175-1178.
- Vakil JJ, O'Reilly MP, Sutter EG, Mears SC, Belko SM, Khanuja HS. Knee arthrotomy repair with a continuous barbed suture: a biomechanical study. J Arthroplasty. 2011;26(5):710-713.
- Nonnenman H. 100326296: Time zero tissue holding - Competitive claims comparisons for STRATAFIX Knotless Tissue Control Devices vs various products. 2015. Ethicon, Inc.
- Sutton N, Schmitz N, Johnston S. Comparing outcomes between barbed and conventional sutures in patients undergoing knee or hip arthroplasty. J Comp Eff Res. 2018;7(10):975-987.
- Edmiston CE, Seabrook GR, Goheen MP, et al. Bacterial adherence to surgical sutures: can antibacterial-coated sutures reduce the risk of microbial contamination? J Am Coll Surg. 2006;203(4):481-489.
- Edmiston CE, Daoud FC, Leaper D. Is there an evidence-based argument for embracing an antimicrobial (triclosan)-coated suture technology to reduce the risk for surgical-site infections?: A meta-analysis. Surgery. 2013;154:89-100.
- Leaper DJ, Edmiston CE Jr, Holy CE. Meta-analysis of the potential economic impact following introduction of absorbable antimicrobial sutures. Br J Surg. 2017;104(2):e134-e144. doi:10.1002/bjs.10443.
- Apisarnthanarak A, Singh N, Bandong AN, et al. Triclosan-coated sutures reduce the risk of surgical site infections: a systematic review and meta-analysis. Infect Control Hosp Epidemic. 2015;36:169-179.
- Chang WK, Srinivasa S, Morton R, et al. Triclosan-impregnated sutures to decrease surgical site infections: systematic review and meta-analysis of randomised trials. Ann Surg. 2012;255(5):854-859.
- Daoud FC, Edmiston CE Jr, Leaper D. Meta-analysis of prevention of surgical site infections following incision closure with triclosan-coated sutures: robustness to new evidence. Surg Infect (Larchmt). 2014;15(3):165-181.
- Daoud FC. Systematic literature review update of the PROUD Trial: potential usefulness of a collaborative database. Surg Infect (Larchmt). 2014;15(6):857-858.
- Guo J, Pan LH, Li YX, et al. Efficacy of triclosan- coated sutures for reducing risk of surgical site infection in adults: a meta-analysis of randomised clinical trials. J Surg Res. 2016; 201(1):105-117.
- Sajid MS, Craciunas L, Sains P, et al. Use of antibacterial sutures for skin closure in controlling surgical site infections: a systematic review of published randomised, controlled trials. Gastroenterol Rep (Oxf). 2013;1(1):42-50.
- Sandini M, Mattavelli I, Nespoli L, Uggeri F, Gianotti L. Systematic review and meta-analysis of sutures coated with triclosan for the prevention of surgical site infection after elective colorectal surgery according to the PRISMA statement. Medicine (Baltimore). 2014;95(35):e4057. doi:10.1097/MD.0000000000004057.
- Wang ZX, Jiang CP, Cao Y, Ding YT. Systematic review and meta-analysis of triclosan-coated sutures for the prevention of surgical-site infection. Br J Surg. 2013;100(4):465-473.
- Wu X, Kubilay NZ, Ren J, et al. Antimicrobial-coated sutures to decrease surgical site infections: a systematic review and meta-analysis. Eur J Clin Microbiol Infect Dis. 2017;36(1):19-32.
- Ahmed I, Boulton AJ, Rizvi S, et al. The use of triclosan-coated sutures to prevent surgical site infections: a systematic review and meta-analysis of the literature. BMJ Open. 2019;9:e029727. doi:10.1136/bmjopen-2019-029727.
- de Jonge SW, Atema JJ, Solomkin JS, Boermeester MA.Meta-analysis and trial sequential analysis of triclosan-coated sutures for the prevention of surgical site infection.Brit J Surg. 2017;ePub DOI: 10.1002 bjs.10445.
- Berrios-Torres SI, Umscheid CA, Bratzler DW, et al. Centers for disease control and prevention guideline for the prevention of surgical site infection, 2017. JAMA Surg. 2017;152(8):784-791.
- Ban KA, Minei JP, Laronga C, et al. American College of Surgeons and Surgical Infection Society: surgical site infection guidelines, 2016 update. J Am Coll Surg. 2017; 224(1):59-74.
- NICE Guideline Updates Team (UK). Surgical site infection: prevention and treatment. NICE website. https://www.nice.org.uk/guidance/ng125/chapter/Recommendations#closuremethods. Accessed April 3, 2020.
- World Health Organisation. Global guidelines for the prevention of surgical site infection. https://apps.who.int/iris/bitstream/handle/10665/250680/9789241549882-eng.pdf?sequence=8. Published November 2016. Accessed April 3, 2020.
- Prevention of postoperative wound infections. Recommendation of the Committee for Hospital Hygiene and Infection Prevention (KRINKO) at the Robert Koch Institute. Bundesgesundheitsbl. 2018;61(4):448-473.
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