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Ethicon has pioneered advances in wound closure which have improved patient outcomes in Australia since 1931.
Ethicon is leading advancements in wound closure with products that are transforming surgery and improving patient outcomes. Our products are designed to:
the risk of complications
operative time to improve hospital efficiencies
DERMABOND® PRINEO® Skin Closure System
The only skin closure device that combines the proven strength, flexibility, and antimicrobial protection of DERMABOND® Topical Skin Adhesive with the added support and security of a self-adhering mesh to further facilitate both wound-edge approximation and an optimal healing environment, which may be particularly useful in surgeries such as hip and knee arthroplasty as well as caesarean section.1-2
STRATAFIX™ Knotless Tissue Control Devices
STRATAFIX™ barbed closure devices deliver more efficiency and strengthƗ than traditional suturing – without knot-related complications.2-4 Compared to traditional sutures,4-6 STRATAFIX™ reduced length of stay7 and time in operating room.3
Plus Antibacterial Sutures
Ethicon’s Plus Antibacterial Sutures are the only triclosan-coated sutures commercially available worldwide and are backed by a large body of evidence.8-20 Meta-analysis showed a 28% reduction in surgical site infection (SSI) risk with triclosan-coated.21§|| Triclosan-coated sutures are endorsed by global health authorities.22-26
*As shown in a study comparing STRATAFIX® Knotless Tissue Control Device with conventional sutures in spinal surgery.
†Refers to STRATAFIX™ Symmetric PDS™ Plus Knotless Tissue Control Device only.
‡Guidelines on reducing the risk of surgical site infections are general to triclosan-coated sutures and are not specific to any one brand.
§In a meta-analysis of 21 randomised clinical trials (RCTs), 6462 patients, 95% Cl: (14, 40%), P<0.001.
||All triclosan-coated sutures in these RCTs were Ethicon Plus Antibacterial Sutures (MONOCRYL® Plus Antibacterial [poliglecaprone 25) Suture, Coated VICRYL® Plus Antibacterial [polyglactin 910) Suture, and PDS® Plus Antibacterial [polydioxanone] Suture).
- Ethicon Inc. DERMABOND® PRINEO® Skin Closure System (22 cm) Instructions for Use. LAB100114233v2. 5/15.
- Data on File. Ethicon, Inc. Su. 06TR071 Study Report for in vitro evaluation of microbial barrier properties of DERMABOND ProTape. (Claim 043324-151113).
- Johnston S, Chen B, Tommaselli G, Jain S, Pracyk J. Barbed and conventional sutures in spinal surgery patients: an economic and clinical outcomes comparison. J Wound Care. 2020;29(5):S9-S20.
- Moran ME, Marsh C, Perrotti M. Bidirectional-barbed sutured knotless running anastomosis v classic Van Velthoven suturing in a model system. J Endourol. 2007;21(10):1175-1178.
- Vakil JJ, O'Reilly MP, Sutter EG, Mears SC, Belko SM, Khanuja HS. Knee arthrotomy repair with a continuous barbed suture: a biomechanical study. J Arthroplasty. 2011;26(5):710-713.
- Nonnenman H. 100326296: Time zero tissue holding - Competitive claims comparisons for STRATAFIX Knotless Tissue Control Devices vs various products. 2015. Ethicon, Inc.
- Sutton N, Schmitz N, Johnston S. Comparing outcomes between barbed and conventional sutures in patients undergoing knee or hip arthroplasty. J Comp Eff Res. 2018;7(10):975-987.
- Edmiston CE, Seabrook GR, Goheen MP, et al. Bacterial adherence to surgical sutures: can antibacterial-coated sutures reduce the risk of microbial contamination? J Am Coll Surg. 2006;203(4):481-489.
- Edmiston CE, Daoud FC, Leaper D. Is there an evidence-based argument for embracing an antimicrobial (triclosan)-coated suture technology to reduce the risk for surgical-site infections?: A meta-analysis. Surgery. 2013;154:89-100.
- Leaper DJ, Edmiston CE Jr, Holy CE. Meta-analysis of the potential economic impact following introduction of absorbable antimicrobial sutures. Br J Surg. 2017;104(2):e134-e144. doi:10.1002/bjs.10443.
- Apisarnthanarak A, Singh N, Bandong AN, et al. Triclosan-coated sutures reduce the risk of surgical site infections: a systematic review and meta-analysis. Infect Control Hosp Epidemic. 2015;36:169-179.
- Chang WK, Srinivasa S, Morton R, et al. Triclosan-impregnated sutures to decrease surgical site infections: systematic review and meta-analysis of randomised trials. Ann Surg. 2012;255(5):854-859.
- Daoud FC, Edmiston CE Jr, Leaper D. Meta-analysis of prevention of surgical site infections following incision closure with triclosan-coated sutures: robustness to new evidence. Surg Infect (Larchmt). 2014;15(3):165-181.
- Daoud FC. Systematic literature review update of the PROUD Trial: potential usefulness of a collaborative database. Surg Infect (Larchmt). 2014;15(6):857-858.
- Guo J, Pan LH, Li YX, et al. Efficacy of triclosan- coated sutures for reducing risk of surgical site infection in adults: a meta-analysis of randomised clinical trials. J Surg Res. 2016; 201(1):105-117.
- Sajid MS, Craciunas L, Sains P, et al. Use of antibacterial sutures for skin closure in controlling surgical site infections: a systematic review of published randomised, controlled trials. Gastroenterol Rep (Oxf). 2013;1(1):42-50.
- Sandini M, Mattavelli I, Nespoli L, Uggeri F, Gianotti L. Systematic review and meta-analysis of sutures coated with triclosan for the prevention of surgical site infection after elective colorectal surgery according to the PRISMA statement. Medicine (Baltimore). 2014;95(35):e4057. doi:10.1097/MD.0000000000004057.
- Wang ZX, Jiang CP, Cao Y, Ding YT. Systematic review and meta-analysis of triclosan-coated sutures for the prevention of surgical-site infection. Br J Surg. 2013;100(4):465-473.
- Wu X, Kubilay NZ, Ren J, et al. Antimicrobial-coated sutures to decrease surgical site infections: a systematic review and meta-analysis. Eur J Clin Microbiol Infect Dis. 2017;36(1):19-32.
- Ahmed I, Boulton AJ, Rizvi S, et al. The use of triclosan-coated sutures to prevent surgical site infections: a systematic review and meta-analysis of the literature. BMJ Open. 2019;9:e029727. doi:10.1136/bmjopen-2019-029727.
- de Jonge SW, Atema JJ, Solomkin JS, Boermeester MA.Meta-analysis and trial sequential analysis of triclosan-coated sutures for the prevention of surgical site infection.Brit J Surg. 2017;ePub DOI: 10.1002 bjs.10445.
- Berrios-Torres SI, Umscheid CA, Bratzler DW, et al. Centers for disease control and prevention guideline for the prevention of surgical site infection, 2017. JAMA Surg. 2017;152(8):784-791.
- Ban KA, Minei JP, Laronga C, et al. American College of Surgeons and Surgical Infection Society: surgical site infection guidelines, 2016 update. J Am Coll Surg. 2017; 224(1):59-74.
- NICE Guideline Updates Team (UK). Surgical site infection: prevention and treatment. NICE website. https://www.nice.org.uk/guidance/ng125/chapter/Recommendations#closuremethods. Accessed April 3, 2020.
- World Health Organisation. Global guidelines for the prevention of surgical site infection. https://apps.who.int/iris/bitstream/handle/10665/250680/9789241549882-eng.pdf?sequence=8. Published November 2016. Accessed April 3, 2020.
- Prevention of postoperative wound infections. Recommendation of the Committee for Hospital Hygiene and Infection Prevention (KRINKO) at the Robert Koch Institute. Bundesgesundheitsbl. 2018;61(4):448-473.
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