See why DERMABOND® PRINEO® Skin Closure System is an ideal way to heal1-6

Bacteria Barrier icon

Forms a lightweight, flexible seal over your incision to protect it from bacteria2,4

Puncture icon.png

Unlike stitches and staples, DERMABOND PRINEO System doesn't puncture your skin, and leaves a better-looking scar than staples1,2

Shower icon

Caring for your incision is simple with no bandages to change, no staples to remove, and no waiting to shower2,7,11



  • DERMABOND PRINEO System is used instead of staples or stitches to close your skin incision after surgery2,4  
  • It consists of a lightweight mesh that’s applied over your incision, then coated with a skin adhesive to create a strong, flexible seal that protects against water and bacteria2,4 
  • There are no dressings to change, which leads to a more comfortable recovery than stitches and staples1,7
A bacteria blocker for your incision

A bacteria blocker for your incision

  • With DERMABOND PRINEO System you can be confident that your incision is protected4,8 
  • The mesh and adhesive interact to create a waterproof barrier against the kinds of bacteria most often associated with post-surgical infections4,8
  • DERMABOND PRINEO System is breathable—even though bacteria and water can't get in, excess moisture from the incision can evaporate, creating an ideal healing environment4,8,9
knee replacement closure comparison with dermabond prineo and staples

Look as good as you feel

  • Leave no tracks! Unlike stitches and staples, DERMABOND PRINEO System doesn't leave railroad track scars10
  • Market research shows the vast majority of surgeons felt that DERMABOND PRINEO System led to better scar appearance compared to staples, and patients agreed they were more satisfied with the look of their scar1*

Ask your doctor about DERMABOND PRINEO System

smiling doctor holding arm of patient

Caring for your incision with DERMABOND PRINEO System

  • Until your healthcare professional determines that your incision is adequately healed, keep your DERMABOND PRINEO System in place, usually for 7-14 days2
  • Don’t scratch, rub or pick at it. If it loosens or comes off before that time, let your doctor know
  • Don’t apply topical lotions, ointments, or liquids
  • Avoid heavy exercise that could put stress on your incision and ask your doctor when you can get back to your normal activities2


* Double-blinded quantitative market research study comparing patient and surgeon experience with DERMABOND PRINEO System and skin staples in total knee arthroplasty. N=88 patients. N=83 orthopaedic surgeons. 90% c.I. Fielded June/July 2017.

1. PRINEO Claims Research Quant Detail. August 16, 2017. Ethicon, Inc.

2. DERMABOND® PRINEO® Skin Closure System Instructions for Use. 2010. Ethicon, Inc.

3. Sutton N, Schmitz ND, Johnston SS. Economic and clinical comparison of 2-octyl cyanoacrylate/polymer mesh tape with skin staples in total knee replacement. J Wound Care. 2018;27(Sup4):S12-S22.  

4. Kumar A. Completion report for design verification testing for DERMABOND™ PRINEO™ 22 cm skin closure system (DP22) AST-2014-0060, Version 2. 2016. Ethicon, Inc.

5. Bhende S. In-vitro study to evaluate the ability of DERMABOND™ PRINEO™ Skin Closure System to kill bacteria on contact. 2012. Ethicon, Inc.  

6. Keplinger S. Protocol investigation of the comparison of PRINEO with conventional wound closure techniques. 07PD048. May 18, 2007. Ethicon, Inc.

7. De Cock E, van Nooten F, Mueller K, Tan R. Changing the surgical wound closure management pathway: time and supplies with PRINEO vs. standard of care for abdominoplasty surgery in Germany. Poster presented at: International Society for Pharmacoeconomics and Outcomes Research, 11th Annual European Congress: November 2008; Athens, Greece.  

8. Su W. Study report for in vitro evaluation of microbial barrier properties of DERMABOND® ProTape. Report 06TR071. December 4, 2006. Ethicon, Inc.  

9. Kannon GA, Garret AB. Moist wound healing with occlusive dressings. Dermatol Surg. 1995;21(7):583-590.

10. Mubarak L, Al-Haddab M. Cutaneous wound closure materials: an overview and update. J Cutan Aesthet Surg. 2013; Oct-Dec; 6(4): 178–188.

11. If directed by your physician.