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Ethicon’s Plus Sutures
Ethicon’s Plus Sutures
Become the First and Only Sutures¥ with Antibacterial Protection recommended for use in NHS by NICE Medical Technologies guidance.1
Note: Image for illustrative purposes only
We are inspired by the opportunity to work together to advance patient care
Working together, we can deliver innovative solutions to today's healthcare challenges to advance patient care and deliver clinical and economic value to healthcare systems throughout the world.
“Plus Sutures are cost saving compared with non-triclosan absorbable sutures by an average of £13.62 per patient.* These savings are from reduced surgical site infections.”1§
NICE Medical Technologies Guidance | Published 28 June 2021
“The report indicates that by preventing surgical site infections, using Plus Sutures results in potential environmental benefits to the NHS in England.”1
NICE Medical Technologies Guidance | Published 28 June 2021
NOTE: Prevention of surgical site infection by using Plus Sutures is not an approved product claim by Ethicon, and can therefore not be actively promoted.
NICE Medical Technology Guidance:
Plus Sutures for Preventing Surgical Site Infection1
NOTE: Prevention of surgical site infection by using Plus Sutures is not an approved product claim by Ethicon, and can therefore not be actively promoted.
ETHICON Plus Antibacterial Sutures
Plus Sutures – the only sutures with Triclosan available worldwide with antibacterial protection offered by IRGACARE®† MP (Triclosan).**2
Triclosan-coated Sutures
Triclosan-coated sutures have been shown in multiple meta-analyses to reduce the risk of SSIs by 28%3-5
“Plus Sutures are cost-saving compared with non-Triclosan absorbable sutures by an average of £13.62 per patient.*
These savings are from reduced surgical site infections.”1
NICE Medical Technologies Guidance | Published 28 June 2021
Global Health Authorities - Statements on Triclosan-coated Sutures
World Health Organization 20166
The panel suggests the use of Triclosan-coated sutures for reducing the risk of SSI, independent of the type of surgery (conditional recommendation, moderate quality of evidence).6
Centre for Disease Control and Prevention, 20177
Consider the use of Triclosan-coated sutures for the prevention of SSI.7
NOTE: Prevention of surgical site infection by using Plus Sutures is not an approved product claim by Ethicon, and can therefore not be actively promoted.
American College of Surgeons/Surgical Infection Society, 2016
SSI-guidelines8
Triclosan antibacterial suture use is recommended for wound closure in clean and clean-contaminated abdominal cases when available.8
Local Health Authorities - Statements on Triclosan-coated Sutures: UK, Germany & European Network
NICE Guidelines Update 20199
When using sutures, consider antimicrobial Triclosan-coated sutures, especially for paediatric surgery, to reduce the risk of surgical site infection (2019).9
Commission for Hospital Hygiene and Infection Prevention 201810
Antiseptically coated sutures only reduce the threat of infection where there are high baseline SSI rates, contamination class III and IV surgeries, and patients with multiple morbidities (Cat. II).10
European Network for Health Technology Assessment 201711
A statistically significant benefit of Triclosan-coated sutures in reducing the risk of total incisional SSI was demonstrated in our SR/MA# based on moderate quality RCTs Data.11
Country Specific Case Stories
ETHICON Plus Antibacterial Sutures
UK Case Story
Use of ETHICON Plus Antibacterial Sutures funded by the Innovation and Technology Payment (ITP) to support a reduction in Surgical Site Infection (SSI) within a National Health Service England (NHSE) Trust.
ETHICON Plus Antibacterial Sutures
Czech Republic Case Story
Use of ETHICON Plus Antibacterial Sutures as part of an infection prevention care bundle in a value-based agreement to support a Surgical Site Infection (SSI) reduction program in a Czech Republic university teaching hospital.
Ethicon’s new patient pathway programmes
including care4today® recovery, a communication tool for the healthcare team to:
• Monitor patient and wound recovery remotely
• Access to real world data in real time
Designed for ease of use for both HCPs and patients:
• Patients get questions by notifications
• HCPs may collect high quality data to support future patient outcomes
MONOCRYL™ Plus Antibacterial (poliglecaprone 25) Suture
Coated VICRYL™ Plus Antibacterial (polyglactin 910) Suture
PDS™ Plus Antibacterial (polydioxanone) Suture
We are inspired by the opportunity to work together to advance patient care
Working together, we can deliver innovative solutions to today's healthcare challenges to advance patient care and deliver clinical and economic value to healthcare systems throughout the world.
Helpful Links
ESCP Congress
Wound Closure Family
Ethicon Home
Ethicon Customer Support
References
* By using Plus Sutures compared with non-triclosan absorbable sutures, likely to be conservative.
** There are no competitive Triclosan coated sutures that have both FDA clearance and CE Mark as of May 2022
† A trademark of BASF .
# Systematic Review/Meta-Analysis.
§Cost savings will vary by surgery type and baseline risk of surgical site infection
¥ As of August 2021
1. © NICE 2021. MEDICAL TECHNOLOGY GUIDANCE: PLUSSUTURES FOR PREVENTING SURGICAL SITE INFECTION. Available from: nice.org.uk/guidance/MTG59Accessed on: 28 June 2021. All rightsreserved. Subject to Notice of rights. NICE guidance is prepared for the National Health Service in England. All NICE guidance is subject to regular review and may be updated or withdrawn. NICE accepts no responsibility for the use of its content in this product/publication
2. Ethicon, Market intelligence and internal knowledge (144092-220815)
3. de JongeS, AtemaJ, SolomkinJ and BoermeesterM, Meta-Analysis and trial sequential analysis of triclosan-coated sutures for the prevention of surgical-site infection. 2017; BJS 104 e118-e133. (144091-200619)
4. Wang Z, Jiang C, Cao Y, Ding Y. Systematic review and meta-analysis of Triclosan-coated sutures for prevention of surgical-site infection. Br J Surgery 2013; 100:465-474. (144091-200619)
5. Edmiston C, Daoud F, Leaper D. Is there an evidence-based argument for embracing an antimicrobial (Triclosan)-coated suture technology to reduce the risk for surgical-site infections? A meta-analysis. Surgery 2013; 154: 89-100. (144091-200619)
6. World Health Organization. Global guidelines for the prevention of surgical site infection.https://apps.who.int/iris/bitstream/handle/10665/250680/9789241549882-eng.pdf?sequence=8. Published November 2016. Accessed April 3, 2020.
7. Berrios-Torres S, UmscheidC, BratzlerD, et al. Centers for disease control and prevention guideline for the prevention of surgical site infection, 2017. JAMA Surg. 2017;152(8):784-791.
8. Ban K, MineiJ, LarongaC, et al. American college of surgeons and surgical infection society: surgical site infection guidelines, 2016 update. J Am CollSurg. 2017; 224(1):59-74.
9. NICE Guideline Updates Team (UK). Surgical site infection: prevention and treatment. NICE website. https://www.nice.org.uk/guidance/ng125/chapter/Recommendations#closuremethods. Accessed July 20, 2021.
10. Prevention of postoperative wound infections. Recommendation of the Committee for Hospital Hygiene and Infection Prevention (KRINKO) at the Robert Koch Institute. Bundesgesundheitsbl. 2018;61(4):448-473.
11. EUnetHTA, Rapid assessment of JA3 WP4 on “Antibacterial-Coated Sutures Versus Non-Antibacterial-Coated Sutures For The Prevention Of Abdominal, Superficial And Deep Incisional, Surgical Site Infection (SSI) March 2017, V1.4.
RESOURCES FOR PAGE
Ethicon, Approved EMEA/UK NICE External Summary of NICE PLUS MTG: 180931-210623. Expiry 28 June,2023.
Ethicon, Approved EMEA/UK Antibacterial Sutures VR video: 137522-200420. Expiry 28 June,2024
Ethicon, Approved EMEA EXPECT MORE PLUS A UK CASE STUDY UK Story: 161984-201207. Expiry 6 July,2023
Ethicon, Approved EMEA EXPECT MORE CZECH STUDY: 172550-210331. Expiry 7 July,2023
Ethicon, Approved EMEA/UK Care4Today Recovery video: 181683-210630. Expiry 27 July,2023
Disclaimer
The information contained herein is exclusively addressed to health professionals.
De volgende informatie is alleen bestemd voor beroepsbeoefenaren in de gezondheidszorg.
Les informations contenues ci-dessus sont exclusivement destinées aux professionnels de santé.
For full product details, including warnings, precautions, contraindications and side effects, please consult the latest Instructions for Use, where applicable.
Raadpleeg de meest recente gebruiksaanwijzing voor de volledige productdetails, inclusief waarschuwingen, voorzorgsmaatregelen, contra-indicaties en bijwerkingen, indien van toepassing.
Pour connaitre les précautions d'emploi, les indications et contre-indications, les effets secondaires merci de consulter la dernière version de la notice d'utilisation.
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