Patient Inclusion and Exclusion Criteria1

Key Inclusion Criteria

  • Documented symptomatic persistent AF, defined as sustained episodes lasting longer than 7 days but less than 1 year
  • Nonresponse or intolerance to at least one Class I or III AAD

Key Exclusion Criteria

  • Left ventricular ejection fraction <40%
  • Left atrial diameter ≥50 mm
  • Previous AF ablation or cardiac surgery
  • NYHA class III or IV
  • Documented left atrial thrombus within 48 hours of procedure
  • Myocardial infarction within the previous 2 months
  • Thromboembolic event in the previous 12 months